The prominent events in the generation of bacterial resistance include inactivation of the porin channel, modification of antibiotic targets, and neutralizing antibiotic efficacy through enzymatic action.
It can be developed either intrinsically by natural recombination and integration into the bacterial genome, or it can be acquired through horizontal gene mutation events such as conjugation, transformation, and transduction.
Antibiotic resistance is defined as the genetic ability of bacteria to encode the resistance genes that counterfeit the inhibitory effect of potential antibiotics for survival.
